"The combination of resveratrol and grape seed extract is very effective at killing colon cancer cells," said Jairam K.P. Vanamala from the Institute. The researchers suggest that the findings could pave the way for clinical testing of the compounds on human colon cancer, which is the second most common cancer in women and the third in men. If successful, the compounds could then be used in creating pills to help prevent colon cancer and lessen the recurrence of the disease in colon cancer survivors.
(Also read: 7 Amazing Benefits of Grapes for Health and Skin)
Resveratrol is a powerful antioxidant that fights against free radicals; Image credit: Istock
According to the researchers, cancer stem cells are capable of self-renewal, cellular differentiation and maintain their stem cell-like characteristics even after invasion and metastasis. When taken separately in low doses, resveratrol and grape seed extract are not as effective against cancer stem-cell suppression as when they are combined together.
"This also connects well with a plant-based diet that is structured so that the person is getting a little bit of different types of plants, of different parts of the plant and different colors of the plant," said Vanamala.
During their experiments conducted on mice, they found that the incidence of tumors was suppressed in the mice consuming the grape compounds alone by 50 percent.
Inputs from ANI